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Optimal cut-point definition in biomarkers: the case of censored failure time outcome

BACKGROUND: Cut-point finding is a crucial step for clinical decision making when dealing with diagnostic (or prognostic) biomarkers. The extension of ROC-based cut-point finding methods to the case of censored failure time outcome is of interest when we are in the presence of a biomarker, measured...

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Bibliografiske detaljer
Udgivet i:BMC Med Res Methodol
Main Authors: Rota, Matteo, Antolini, Laura, Valsecchi, Maria Grazia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430986/
https://ncbi.nlm.nih.gov/pubmed/25887743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-015-0009-y
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