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Epithelial–Mesenchymal Interactions in Fibrosis and Repair. Transforming Growth Factor-β Activation by Epithelial Cells and Fibroblasts
Transforming growth factor-β (TGF-β) plays a central role in driving tissue fibrosis. TGF-β is secreted in a latent form, held latent by noncovalent association of the active cytokine with a peptide derived from cleavage of the N-terminal domain of the same gene product, and needs to be activated ex...
Kaydedildi:
| Yayımlandı: | Ann Am Thorac Soc |
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| Yazar: | |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Thoracic Society
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430968/ https://ncbi.nlm.nih.gov/pubmed/25830829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201406-245MG |
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