Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver.

Hepatic lipocytes play a central role in the pathogenesis of liver fibrosis, both via production of extracellular matrix proteins and through secretion of matrix metalloproteinases. In this study, we have characterized lipocyte expression and release of tissue inhibitor of metalloproteinases-1 (TIMP...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Iredale, J P, Murphy, G, Hembry, R M, Friedman, S L, Arthur, M J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1634616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115850
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