High-recovery visual identification and single-cell retrieval of circulating tumor cells for genomic analysis using a dual-technology platform integrated with automated immunofluorescence staining

BACKGROUND: Circulating tumor cells (CTCs) are malignant cells that have migrated from solid cancers into the blood, where they are typically present in rare numbers. There is great interest in using CTCs to monitor response to therapies, to identify clinically actionable biomarkers, and to provide...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Campton, Daniel E, Ramirez, Arturo B, Nordberg, Joshua J, Drovetto, Nick, Clein, Alisa C, Varshavskaya, Paulina, Friemel, Barry H, Quarre, Steve, Breman, Amy, Dorschner, Michael, Blau, Sibel, Blau, C Anthony, Sabath, Daniel E, Stilwell, Jackie L, Kaldjian, Eric P
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Technical Advance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430903/
https://ncbi.nlm.nih.gov/pubmed/25944336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1383-x
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