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The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

T cells respond to peptide antigen in association with MHC products on antigen-presenting cells (APCs). A number of accessory or costimulatory molecules have been identified that also contribute to T cell activation. Several of the known accessory molecules are expressed by freshly isolated dendriti...

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Bibliographische Detailangaben
Hauptverfasser: Young, J W, Koulova, L, Soergel, S A, Clark, E A, Steinman, R M, Dupont, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC443085/
https://ncbi.nlm.nih.gov/pubmed/1378854
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