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The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

T cells respond to peptide antigen in association with MHC products on antigen-presenting cells (APCs). A number of accessory or costimulatory molecules have been identified that also contribute to T cell activation. Several of the known accessory molecules are expressed by freshly isolated dendriti...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Young, J W, Koulova, L, Soergel, S A, Clark, E A, Steinman, R M, Dupont, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1378854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115840
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