Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Up-Regulating Cystathionine β-Synthase Expression

Estrogens dramatically dilate numerous vascular beds with the greatest response in the uterus. Endogenous hydrogen sulfide (H(2)S) is a potent vasodilator and proangiogenic second messenger, which is synthesized from L-cysteine by cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE). We hy...

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Publicado en:Endocrinology
Autores principales: Lechuga, Thomas J., Zhang, Hong-hai, Sheibani, Lili, Karim, Muntarin, Jia, Jason, Magness, Ronald R., Rosenfeld, Charles R., Chen, Dong-bao
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430606/
https://ncbi.nlm.nih.gov/pubmed/25825818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1086
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