Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200

The aim of this preclinical study was to evaluate the characteristics of the monoclonal antibody Rebmab200, which is a humanized version of the ovarian-specific murine antibody MX35. This investigation contributes to the foundation for future clinical α-radioimmunotherapy of minimal residual ovarian...

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Publicado en:PLoS One
Main Authors: Lindegren, Sture, Andrade, Luciana N. S., Bäck, Tom, Machado, Camila Maria L., Horta, Bruno Brasil, Buchpiguel, Carlos, Moro, Ana Maria, Okamoto, Oswaldo Keith, Jacobsson, Lars, Cederkrantz, Elin, Washiyama, Kohshin, Aneheim, Emma, Palm, Stig, Jensen, Holger, Tuma, Maria Carolina B., Chammas, Roger, Hultborn, Ragnar, Albertsson, Per
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430291/
https://ncbi.nlm.nih.gov/pubmed/25970341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126298
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