Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

Enhanced glutamatergic transmission in the nucleus accumbens (NAc), a region critical for reward and motivation, has been implicated in the pathophysiology of depression; however, the afferent source of this increased glutamate tone is not known. The NAc receives glutamatergic inputs from the medial...

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Publicat a:Nat Commun
Autors principals: Bagot, Rosemary C., Parise, Eric M., Peña, Catherine J., Zhang, Hong-Xing, Maze, Ian, Chaudhury, Dipesh, Persaud, Brianna, Cachope, Roger, Bolaños-Guzmán, Carlos A., Cheer, Joseph, Deisseroth, Karl, Han, Ming-Hu, Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430111/
https://ncbi.nlm.nih.gov/pubmed/25952660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8062
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