Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state.

To explore the mechanisms of antigen-specific immune unresponsiveness seen in microfilaremic patients with bancroftian filariasis, T and B cell precursor frequency analysis was performed using PBMC from individuals with either asymptomatic microfilaremia (MF, n = 7) or chronic lymphatic obstruction...

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Bibliographic Details
Main Authors: King, C L, Kumaraswami, V, Poindexter, R W, Kumari, S, Jayaraman, K, Alling, D W, Ottesen, E A, Nutman, T B
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC443009/
https://ncbi.nlm.nih.gov/pubmed/1569183
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