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Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins

BACKGROUND: Autism spectrum disorders (ASDs) are more prevalent in males, suggesting a multiple threshold liability model in which females are, on average, protected by sex-differential mechanisms. Under this model, autistic females are predicted to carry a more penetrant risk variant load than male...

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Detalhes bibliográficos
Publicado no:Mol Autism
Main Authors: Werling, Donna M, Geschwind, Daniel H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429923/
https://ncbi.nlm.nih.gov/pubmed/25973164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-015-0004-5
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