De novo Reconstruction of Adipose Tissue Transcriptomes Reveals Novel Long Non-coding RNAs that Regulate Brown Adipocyte Development

Brown adipose tissue (BAT) protects against obesity by promoting energy expenditure via uncoupled respiration. To uncover BAT-specific long non-coding RNAs (lncRNAs), we used RNA-seq to reconstruct de novo transcriptomes of mouse brown, inguinal white, and epididymal white fat and identified ~1500 l...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Alvarez-Dominguez, Juan R., Bai, Zhiqiang, Xu, Dan, Yuan, Bingbing, Lo, Kinyui Alice, Yoon, Myeong Jin, Lim, Yen Ching, Knoll, Marko, Slavov, Nikolai, Chen, Shuai, Peng, Chen, Lodish, Harvey F., Sun, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429916/
https://ncbi.nlm.nih.gov/pubmed/25921091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.04.003
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