FTY720 attenuates excitotoxicity and neuroinflammation

BACKGROUND: FTY720 (fingolimod, Gilenya™), a structural analog of sphingosine-1-phosphate (S1P), is the first oral drug approved for treatment the relapsing-remitting form of multiple sclerosis (MS), and its efficacy has been related to induced lymphopenia and consequent immunosuppression via modula...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Cipriani, Raffaela, Chara, Juan Carlos, Rodríguez-Antigüedad, Alfredo, Matute, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429813/
https://ncbi.nlm.nih.gov/pubmed/25953296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0308-6
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