Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis.
The N-terminal 392 amino acids of the Drosophila kinesin alpha subunit (designated DKH392) form a dimer in solution that releases only one of its two tightly bound ADP molecules on association with a microtubule, whereas a shorter monomeric construct (designated DKH340) releases > or = 95% of its on...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.6865 |
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