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Differential expression of glycosylphosphatidylinositol-anchored proteins in a murine T cell hybridoma mutant producing limiting amounts of the glycolipid core. Implications for paroxysmal nocturnal hemoglobinuria.

A T cell hybridoma mutant, which expressed a markedly reduced level of glycosylphosphatidylinositol (GPI)-anchored proteins on the cell surface, was characterized. The surface expression level of Thy-1 was approximately 17% of the wild-type level, whereas the surface expression of Ly-6A was approxim...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Thomas, L J, Urakaze, M, DeGasperi, R, Kamitani, T, Sugiyama, E, Chang, H M, Warren, C D, Yeh, E T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1532587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115700
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