Selective Hyaluronan–CD44 Signaling Promotes miRNA-21 Expression and Interacts with Vitamin D Function during Cutaneous Squamous Cell Carcinomas Progression Following UV Irradiation

Hyaluronan (HA), the major extracellular matrix component, is often anchored to CD44, a family of structurally/functionally important cell surface receptors. Recent results indicate that UV irradiation (UVR)-induced cutaneous squamous cell carcinomas (SCC) overexpress a variety of CD44 variant isofo...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Bourguignon, Lilly Y. W., Bikle, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429634/
https://ncbi.nlm.nih.gov/pubmed/26029210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00224
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