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31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus.

To assess the rate-limiting step in muscle glycogen synthesis in non-insulin-dependent diabetes mellitus (NIDDM), the concentration of glucose-6-phosphate (G6P) was measured by 31P nuclear magnetic resonance (NMR) during a hyperglycemic-hyperinsulinemic clamp. Six subjects with NIDDM and six age wei...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Rothman, D L, Shulman, R G, Shulman, G I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115686
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