Human growth hormone (hGH) secretion in milk of goats after direct transfer of the hGH gene into the mammary gland by using replication-defective retrovirus vectors.

Mammary-specific promoters have been used in transgenic animals to limit transgene expression to the mammary gland. Gene therapy techniques to target just one organ for introduction of a foreign gene have also been demonstrated. We have directly infused replication-defective retroviruses encoding hG...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Archer, J S, Kennan, W S, Gould, M N, Bremel, R D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.6840
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