Tumor necrosis factor-alpha-mediated decrease in glutathione increases the sensitivity of pulmonary vascular endothelial cells to H2O2.

We examined the effects of tumor necrosis factor-alpha (TNF alpha) stimulation of endothelial cells on the increase in endothelial permeability induced by H2O2. Bovine pulmonary microvascular endothelial cells (BPMVEC) were grown to confluence on a microporous filter and the 125I-albumin clearance r...

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Pubblicato in:	J Clin Invest
Autori principali:	Ishii, Y, Partridge, C A, Del Vecchio, P J, Malik, A B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1541673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115658
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