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A Case of Diverticular Perforation in a Young Patient with Rheumatoid Arthritis on Methotrexate

Background. Disease-modifying antirheumatic drugs (DMARDs), such as methotrexate (MTX), are associated with gastrointestinal toxicity. MTX inhibits dihydrofolate reductase, but it is unclear if polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene predict toxicity. Case. We describe...

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Detalhes bibliográficos
Publicado no:Case Rep Med
Main Authors: Chang, Ian, Guggenheim, Carla, Laird-Fick, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429201/
https://ncbi.nlm.nih.gov/pubmed/26064129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/617268
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