Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion

The CA125 antigen is found in the serum of many patients with serous ovarian cancer and has been widely used as a disease marker. CA125 has been shown to be an independent factor for clinical outcome in this disease. In The Cancer Genome Atlas ovarian cancer project, MUC16 expression levels are freq...

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Publicat a:PLoS One
Autors principals: Rao, Thapi D., Tian, Huasong, Ma, Xun, Yan, Xiujun, Thapi, Sahityasri, Schultz, Nikolaus, Rosales, Nestor, Monette, Sebastien, Wang, Amy, Hyman, David M., Levine, Douglas A., Solit, David, Spriggs, David R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429113/
https://ncbi.nlm.nih.gov/pubmed/25965947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126633
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