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Early pregnancy IGF-I and placental GH and risk of epithelial ovarian cancer: A nested case-control study

Insulin-like growth factor-I (IGF-I) signaling may promote ovarian tumor development by exerting mitotic, anti-apoptotic, and pro-angiogenic effects. During pregnancy, maternal production of IGF-I is regulated by placental growth hormone (GH). Parity is an established protective factor for ovarian c...

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Detalles Bibliográficos
Publicado en:Int J Cancer
Main Authors: Schock, Helena, Fortner, Renée T, Surcel, Heljä-Marja, Grankvist, Kjell, Pukkala, Eero, Lehtinen, Matti, Lundin, Eva
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428944/
https://ncbi.nlm.nih.gov/pubmed/25516257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29387
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