Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation.

Peripheral blood lymphocytes (PBL) were obtained from HIV-1-infected patients at different stages of disease. The absolute number of IgM-, IgG-, and IgA-producing lymphocytes per 10(6) PBL was increased 2.8-, 3.4-, and 1.9-fold, respectively, compared with normal controls. 2-17% of IgG-secreting pat...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shirai, A, Cosentino, M, Leitman-Klinman, S F, Klinman, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1737846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115621
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