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Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington’s Disease Mice

In hereditary neurodegenerative Huntington’s disease (HD), there exists a growing consideration that sleep and circadian dysregulations may be important symptoms. It is not known, however, whether sleep abnormalities contribute to other behavioral deficits in HD patients and mouse models. To determi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lebreton, Fanny, Cayzac, Sebastien, Pietropaolo, Susanna, Jeantet, Yannick, Cho, Yoon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428700/
https://ncbi.nlm.nih.gov/pubmed/25966356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126972
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