An Ex Vivo Model for Studying Hepatic Schistosomiasis and the Effect of Released Protein from Dying Eggs

BACKGROUND: We report the use of an ex vivo precision cut liver slice (PCLS) mouse model for studying hepatic schistosomiasis. In this system, liver tissue is unfixed, unfrozen, and alive for maintenance in culture and subsequent molecular analysis. METHODS AND FINDINGS: Using thick naive mouse live...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: Gobert, Geoffrey N., Nawaratna, Sujeevi K., Harvie, Marina, Ramm, Grant A., McManus, Donald P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428699/
https://ncbi.nlm.nih.gov/pubmed/25965781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003760
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