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p53 Expression by Immunohistochemistry is an Independent Determinant of Survival in Chronic Lymphocytic Leukemia Patients Receiving Frontline Chemo-Immunotherapy

Although chromosome 17p abnormalities and TP53 mutations are purported to be poor prognostic indicators in chronic lymphocytic leukemia (CLL), the significance of p53 expression in CLL has not been defined in patients uniformly treated with chemoimmunotherapy, nor has its utility in combination with...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Schlette, Ellen J, Admirand, Joan, Wierda, William, Abruzzo, Lynne, O'Brien, Susan, Lerner, Susan, Keating, Michael J, Tam, Constantine
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428664/
https://ncbi.nlm.nih.gov/pubmed/19863337
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