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Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells.

The formation of oxygen radicals by phagocytic cells occurs through the activation of a multiple-component NADPH oxidase system. An unidentified low molecular weight GTP-binding protein has been proposed to modulate the activity of the NADPH oxidase. The low molecular weight GTP-binding proteins und...

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Detalhes bibliográficos
Main Authors: Bokoch, G M, Prossnitz, V
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC442866/
https://ncbi.nlm.nih.gov/pubmed/1310693
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