MHC Class II-Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Pro-Atherogenic T Cell Immunity

BACKGROUND: Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive. METHODS AND RESULTS: Here, we used genetic approaches to investigate the role of pDCs in a...

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Veröffentlicht in:Circulation
Hauptverfasser: Sage, Andrew, Murphy, Deirdre M., Maffia, Pasquale, Masters, Leanne M., Sabir, Suleman R., Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Ait-Oufella, Hafid, Grassia, Gianluca, Harrison, James E., Ludewig, Burkhard, Reith, Walter, Hansson, Göran K., Reizis, Boris, Hugues, Stéphanie, Mallat, Ziad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428652/
https://ncbi.nlm.nih.gov/pubmed/25223984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.011090
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