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Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells.

To examine the role of protein kinase C as a chronic regulator of proximal tubule Na/H antiporter activity, the effect of phorbol 12-myristate 13-acetate (PMA) on the Na/H antiporter was studied in cultured proximal tubule cells. Short-term activation of protein kinase C by 5 min exposure to PMA cau...

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Vydáno v:J Clin Invest
Hlavní autoři: Horie, S, Moe, O, Miller, R T, Alpern, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442861/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115594
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