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Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans

Proteome stability is central to cellular function and the lifespan of an organism. This is apparent in muscle cells, where incorrect folding and assembly of the sarcomere contributes to disease and aging. Apart from the myosin-assembly factor UNC-45, the complete network of chaperones involved in a...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Frumkin, Anna, Dror, Shiran, Pokrzywa, Wojciech, Bar-Lavan, Yael, Karady, Ido, Hoppe, Thorsten, Ben-Zvi, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428482/
https://ncbi.nlm.nih.gov/pubmed/25988162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00021
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