The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors

Pontin and Reptin are related partner proteins belonging to the AAA+ (ATPases Associated with various cellular Activities) family. They are implicated in multiple and seemingly unrelated processes encompassing the regulation of gene transcription, the remodeling of chromatin, DNA damage sensing and...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Matias, Pedro M., Baek, Sung Hee, Bandeiras, Tiago M., Dutta, Anindya, Houry, Walid A., Llorca, Oscar, Rosenbaum, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428354/
https://ncbi.nlm.nih.gov/pubmed/25988184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00017
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