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Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs.

To study the roles of substance P and endogenous neutral endopeptidase in mediating cough, we measured cough responses in awake guinea pigs in response to exogenous substance P and capsaicin aerosols in the presence and absence of the neutral endopeptidase inhibitors leucine-thiorphan and phosphoram...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Kohrogi, H, Graf, P D, Sekizawa, K, Borson, D B, Nadel, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113827
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