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Functional screening system for yeast-secreted peptides acting on G-protein coupled receptors

We established a novel functional screening system for peptides acting on G-protein coupled receptors (GPCRs). Peptides are a promising drug scaffold because of their intermediate molecular size between that of therapeutic small molecules and antibodies. They also offer potential advantages of targe...

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Foilsithe in:AMB Express
Main Authors: Shigemori, Tomohiro, Kuroda, Kouichi, Ueda, Mitsuyoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427575/
https://ncbi.nlm.nih.gov/pubmed/25992304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-015-0113-8
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