DNA methylation on N(6)-adenine in C. elegans

In mammalian cells, DNA methylation on the 5(th) position of cytosine (5mC) plays an important role as an epigenetic mark. However, DNA methylation was considered to be absent in C. elegans because of the lack of detectable 5mC as well as homologs of the cytosine DNA methyltransferases. Here, using...

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Pubblicato in:Cell
Autori principali: Greer, Eric Lieberman, Blanco, Mario Andres, Gu, Lei, Sendinc, Erdem, Liu, Jianzhao, Aristizábal-Corrales, David, Hsu, Chih-Hung, Aravind, L., He, Chuan, Shi, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427530/
https://ncbi.nlm.nih.gov/pubmed/25936839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.005
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