Biochemical Increase in Phosphorylated Alpha‐Synuclein Precedes Histopathology of Lewy‐Type Synucleinopathies

A key component in Lewy body (LB) pathology in LB disorders is α‐synuclein phosphorylated at serine 129 (pαsyn). However, it is not known if increase in the level of biochemically measurable pαsyn precedes the presence of histologically identified Lewy‐type synucleinopathy (LTS). To gain sights into...

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Библиографические подробности
Опубликовано в: :Brain Pathol
Главные авторы: Lue, Lih‐Fen, Walker, Douglas G., Adler, Charles H., Shill, Holly, Tran, Hung, Akiyama, Haruhiko, Sue, Lucia I., Caviness, John, Sabbagh, Marwan N., Beach, Thomas G.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2012
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427521/
https://ncbi.nlm.nih.gov/pubmed/22369130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00585.x
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