Biochemical Increase in Phosphorylated Alpha‐Synuclein Precedes Histopathology of Lewy‐Type Synucleinopathies

A key component in Lewy body (LB) pathology in LB disorders is α‐synuclein phosphorylated at serine 129 (pαsyn). However, it is not known if increase in the level of biochemically measurable pαsyn precedes the presence of histologically identified Lewy‐type synucleinopathy (LTS). To gain sights into...

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Foilsithe in:Brain Pathol
Main Authors: Lue, Lih‐Fen, Walker, Douglas G., Adler, Charles H., Shill, Holly, Tran, Hung, Akiyama, Haruhiko, Sue, Lucia I., Caviness, John, Sabbagh, Marwan N., Beach, Thomas G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2012
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427521/
https://ncbi.nlm.nih.gov/pubmed/22369130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00585.x
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