Biochemical Increase in Phosphorylated Alpha‐Synuclein Precedes Histopathology of Lewy‐Type Synucleinopathies

A key component in Lewy body (LB) pathology in LB disorders is α‐synuclein phosphorylated at serine 129 (pαsyn). However, it is not known if increase in the level of biochemically measurable pαsyn precedes the presence of histologically identified Lewy‐type synucleinopathy (LTS). To gain sights into...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Lue, Lih‐Fen, Walker, Douglas G., Adler, Charles H., Shill, Holly, Tran, Hung, Akiyama, Haruhiko, Sue, Lucia I., Caviness, John, Sabbagh, Marwan N., Beach, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427521/
https://ncbi.nlm.nih.gov/pubmed/22369130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00585.x
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