Interleukin 1 binds to specific receptors on human keratinocytes and induces granulocyte macrophage colony-stimulating factor mRNA and protein. A potential autocrine role for interleukin 1 in epidermis.

Cultured human keratinocytes have been shown to produce IL-1 alpha and beta mRNA and protein. IL-1 biological activity has been identified in normal human epidermis; in vitro, most biologically active IL-1 resides in a cell-associated compartment. The potential for autocrine effects of IL-1 on human...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kupper, T S, Lee, F, Birchall, N, Clark, S, Dower, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC442749/
https://ncbi.nlm.nih.gov/pubmed/2460504
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