Interleukin 1 binds to specific receptors on human keratinocytes and induces granulocyte macrophage colony-stimulating factor mRNA and protein. A potential autocrine role for interleukin 1 in epidermis.

Cultured human keratinocytes have been shown to produce IL-1 alpha and beta mRNA and protein. IL-1 biological activity has been identified in normal human epidermis; in vitro, most biologically active IL-1 resides in a cell-associated compartment. The potential for autocrine effects of IL-1 on human...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kupper, T S, Lee, F, Birchall, N, Clark, S, Dower, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2460504/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113792
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