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Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface.

Lysine-plasminogen (Lys-PLG), the plasmin-modified form of native glutamic acid-plasminogen (Glu-PLG), displays enhanced binding affinity for fibrin and also enhanced activation by urokinase and tissue plasminogen activator. We previously demonstrated high-affinity, specific, and functional binding...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Hajjar, K A, Nachman, R L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113790
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