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Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis.

Systemic lupus erythematosus (SLE) is associated with the presence of complement proteins and immune complexes in affected organs. Since complement proteins are synthesized in hepatic and extrahepatic sites, we studied a murine model of SLE to ascertain the relative importance of local and humoral (...

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Bibliografiska uppgifter
Huvudupphovsmän: Passwell, J, Schreiner, G F, Nonaka, M, Beuscher, H U, Colten, H R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC442737/
https://ncbi.nlm.nih.gov/pubmed/3183062
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