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Quantification of Histone Deacetylase Isoforms in Human Frontal Cortex, Human Retina, and Mouse Brain

Histone deacetylase (HDAC) inhibition has promise as a therapy for Alzheimer’s disease (AD) and other neurodegenerative diseases. Currently, therapeutic HDAC inhibitors target many HDAC isoforms, a particularly detrimental approach when HDAC isoforms are known to have different and specialized funct...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Anderson, Kyle W., Chen, Junjun, Wang, Meiyao, Mast, Natalia, Pikuleva, Irina A., Turko, Illarion V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427357/
https://ncbi.nlm.nih.gov/pubmed/25962138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126592
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