Astragaloside IV Attenuates Glutamate-Induced Neurotoxicity in PC12 Cells through Raf-MEK-ERK Pathway

Astragaloside IV (AGS-IV) is a main active ingredient of Astragalus membranaceus Bunge, a medicinal herb prescribed as an immunostimulant, hepatoprotective, antiperspirant, a diuretic or a tonic as documented in Chinese Materia Medica. In the present study, we employed a high-throughput comparative...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yue, Rongcai, Li, Xia, Chen, Bingyang, Zhao, Jing, He, Weiwei, Yuan, Hu, Yuan, Xing, Gao, Na, Wu, Guozhen, Jin, Huizi, Shan, Lei, Zhang, Weidong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427284/
https://ncbi.nlm.nih.gov/pubmed/25961569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126603
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