Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia

The structures of three aspartate aminotransferases (AATs) from eukaryotic pathogens were solved within the Seattle Structural Genomics Center for Infectious Disease (SSGCID). Both the open and closed conformations of AAT were observed. Pyridoxal phosphate was bound to the active site via a Schiff b...

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Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Abendroth, Jan, Choi, Ryan, Wall, Abigail, Clifton, Matthew C., Lukacs, Christine M., Staker, Bart L., Van Voorhis, Wesley, Myler, Peter, Lorimer, Don D., Edwards, Thomas E.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2015
Matèries:
Molecular Parasitology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427166/
https://ncbi.nlm.nih.gov/pubmed/25945710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15001831
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