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Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia

The structures of three aspartate aminotransferases (AATs) from eukaryotic pathogens were solved within the Seattle Structural Genomics Center for Infectious Disease (SSGCID). Both the open and closed conformations of AAT were observed. Pyridoxal phosphate was bound to the active site via a Schiff b...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Abendroth, Jan, Choi, Ryan, Wall, Abigail, Clifton, Matthew C., Lukacs, Christine M., Staker, Bart L., Van Voorhis, Wesley, Myler, Peter, Lorimer, Don D., Edwards, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427166/
https://ncbi.nlm.nih.gov/pubmed/25945710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15001831
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