Three Patients Needing High Doses of Valproic Acid to Get Therapeutic Concentrations

Valproic acid (VPA) can autoinduce its own metabolism. Cases requiring VPA doses >4000 mg/day to obtain therapeutic plasma concentrations, such as these 3 cases, have never been published. Case 1 received VPA for seizures and schizophrenia and had >50 VPA concentrations in 4 years. A high dose...

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Bibliografiske detaljer
Udgivet i:Case Rep Psychiatry
Main Authors: Jackson, James, McCollum, Betsy, Ognibene, Judy, Diaz, Francisco J., de Leon, Jose
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427013/
https://ncbi.nlm.nih.gov/pubmed/26000191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/542862
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