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Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes.

Anandamide, an endogenous eicosanoid derivative (arachidonoylethanolamide), binds to the cannabinoid receptor, a member of the G protein-coupled superfamily. It also inhibits both adenylate cyclase and N-type calcium channel opening. The enzymatic synthesis of anandamide in bovine brain tissue was e...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Devane, W A, Axelrod, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8022836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.14.6698
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