Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains.

To define the T-cell receptor signal transduction motif, we have transfected human and murine T-cell lines with a chimeric receptor consisting of the extracellular and transmembrane domains of human CD8 alpha and the membrane-proximal portion of CD3 zeta containing at its C terminus either an 18-ami...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Koyasu, S, Tse, A G, Moingeon, P, Hussey, R E, Mildonian, A, Hannisian, J, Clayton, L K, Reinherz, E L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7517560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.14.6693
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