High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulation

Hyperoxia exposure in mice leads to cardiac hypertrophy and voltage-gated potassium (Kv) channel remodeling. Because redox balance of pyridine nucleotides affects Kv function and hyperoxia alters cellular redox potential, we hypothesized that hyperoxia exposure leads to cardiac ion channel disturban...

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Bibliographic Details
Published in:Toxicol Appl Pharmacol
Main Authors: Chapalamadugu, Kalyan C., Panguluri, Siva K., Bennett, Eric S., Kolliputi, Narasaiah, Tipparaju, Srinivas M.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426884/
https://ncbi.nlm.nih.gov/pubmed/25447406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.019
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