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Combining tree-based and dynamical systems for the inference of gene regulatory networks

Motivation: Reconstructing the topology of gene regulatory networks (GRNs) from time series of gene expression data remains an important open problem in computational systems biology. Existing GRN inference algorithms face one of two limitations: model-free methods are scalable but suffer from a lac...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Huynh-Thu, Vân Anh, Sanguinetti, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426834/
https://ncbi.nlm.nih.gov/pubmed/25573916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu863
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