Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.
Oral tolerance was generated to hen egg white lysozyme in the mouse or to guinea pig myelin basic protein in the rat by a low-dose (1 mg) or a high-dose (5-20 mg) feeding regimen. High doses of antigen induced tolerance characterized by anergy with little or no active suppression and increased secre...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8022835/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.14.6688 |
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