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EZH2 Modulates Angiogenesis In Vitro and in a Mouse Model of Limb Ischemia
Epigenetic mechanisms may regulate the expression of pro-angiogenic genes, thus affecting reparative angiogenesis in ischemic limbs. The enhancer of zest homolog-2 (EZH2) induces thtrimethylation of lysine 27 on histone H3 (H3K27me3), which represses gene transcription. We explored (i) if EZH2 expre...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426795/ https://ncbi.nlm.nih.gov/pubmed/25189741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.163 |
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