Genetic markers in the EET metabolic pathway are associated with outcomes in patients with aneurysmal subarachnoid hemorrhage

Preclinical studies show that epoxyeicosatrienoic acids (EETs) regulate cerebrovascular tone and protect against cerebral ischemia. We investigated the relationship between polymorphic genes involved in EET biosynthesis/metabolism, cytochrome P450 (CYP) eicosanoid levels, and outcomes in 363 patient...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Donnelly, Mark K, Conley, Yvette P, Crago, Elizabeth A, Ren, Dianxu, Sherwood, Paula R, Balzer, Jeffery R, Poloyac, Samuel M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426743/
https://ncbi.nlm.nih.gov/pubmed/25388680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.195
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