Sex differences in ischemic stroke sensitivity are influenced by gonadal hormones, not by sex chromosome complement

Epidemiologic studies have shown sex differences in ischemic stroke. The four core genotype (FCG) mouse model, in which the testes determining gene, Sry, has been moved from Y chromosome to an autosome, was used to dissociate the effects of sex hormones from sex chromosome in ischemic stroke outcome...

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Bibliografische gegevens
Gepubliceerd in:J Cereb Blood Flow Metab
Hoofdauteurs: Manwani, Bharti, Bentivegna, Kathryn, Benashski, Sharon E, Venna, Venugopal Reddy, Xu, Yan, Arnold, Arthur P, McCullough, Louise D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426738/
https://ncbi.nlm.nih.gov/pubmed/25388681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.186
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