Sex differences in ischemic stroke sensitivity are influenced by gonadal hormones, not by sex chromosome complement

Epidemiologic studies have shown sex differences in ischemic stroke. The four core genotype (FCG) mouse model, in which the testes determining gene, Sry, has been moved from Y chromosome to an autosome, was used to dissociate the effects of sex hormones from sex chromosome in ischemic stroke outcome...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Manwani, Bharti, Bentivegna, Kathryn, Benashski, Sharon E, Venna, Venugopal Reddy, Xu, Yan, Arnold, Arthur P, McCullough, Louise D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426738/
https://ncbi.nlm.nih.gov/pubmed/25388681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.186
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