Sex differences in ischemic stroke sensitivity are influenced by gonadal hormones, not by sex chromosome complement

Epidemiologic studies have shown sex differences in ischemic stroke. The four core genotype (FCG) mouse model, in which the testes determining gene, Sry, has been moved from Y chromosome to an autosome, was used to dissociate the effects of sex hormones from sex chromosome in ischemic stroke outcome...

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Bibliografiska uppgifter
I publikationen:J Cereb Blood Flow Metab
Huvudupphovsmän: Manwani, Bharti, Bentivegna, Kathryn, Benashski, Sharon E, Venna, Venugopal Reddy, Xu, Yan, Arnold, Arthur P, McCullough, Louise D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426738/
https://ncbi.nlm.nih.gov/pubmed/25388681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.186
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