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Interleukin 1 stimulates its own receptor expression on human fibroblasts through the endogenous production of prostaglandin(s).

The regulation of interleukin 1 receptor (IL 1R) expression on human dermal fibroblasts was investigated. On exposure to IL 1 for 3 h at 37 degrees C, the capacity of fibroblasts to bind 125I-labeled human recombinant IL 1 alpha (125I-IL 1 alpha) was reduced by 75%. The IL 1 binding capability of th...

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Detalhes bibliográficos
Main Authors: Akahoshi, T, Oppenheim, J J, Matsushima, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC442672/
https://ncbi.nlm.nih.gov/pubmed/2971671
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